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1981年1月～1986年11月,对Baltimore-Wa-shington地区2102例先天性心血管畸形的研究表明,先天性心血管畸形伴染色体异常271例,二者之间存在着某种内在联系。方法本研究采用病例对照法,由所调查地区6个小儿心血管病中心协作进行。凡1岁以内的活产婴儿临床上疑为先天性心血管畸形,经超声心动图、心导管检查、外科手术或尸体解剖证实者均列为病例组
From January 1981 to November 1986, 2102 cases of congenital cardiovascular malformations in the Baltimore-Wa-shington area showed that there were 271 cases of congenital cardiovascular malformations with chromosomal abnormalities, and there was some intrinsic relationship between the two. Methods The case-control study was conducted in this study in collaboration with six pediatric cardiovascular disease centers in the surveyed areas. Where within 1 year of live births clinically suspected congenital cardiovascular malformations, confirmed by echocardiography, cardiac catheterization, surgery or autopsy were included in the case group