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目的探讨胃大部切除术后功能性排空障碍的发生原因,诊断及治疗。方法对1993~1998年施行的256例胃大部切除术的临床资料进行回顾性分析。结果本组共发生功能性排空障碍12例,发生率47%,均发生于术后3~12天。所有病人均经保守治疗治愈出院,833%于1周内治愈,2周内6667%治愈,3周内9167%治愈,所有病人均于32天之内治愈。结论术后残胃和远端空肠正常的运动功能破坏是发生功能性排空障碍的主要原因。消化道造影及胃镜检查是诊断本病及与机械性梗阻鉴别的重要方法。采取非手术治疗一般均可治愈,针对胃排空动力学机制的改变采用促胃肠动力药物可能收到较好的疗效
Objective To investigate the causes, diagnosis and treatment of functional emptying disorder after subtotal gastrectomy. Methods The clinical data of 256 cases of subtotal gastrectomy performed from 1993 to 1998 were analyzed retrospectively. Results There were 12 cases of functional emptying disorder in this group, the incidence was 47%, all of which occurred in 3 to 12 days after operation. All patients were cured by conservative treatment and were discharged. 833% were cured within 1 week, 6667% within 2 weeks and 9167% within 3 weeks. All patients were cured within 32 days. Conclusions The normal dysfunction of the residual gastric and distal jejunum after surgery is the main reason for the occurrence of functional emptying disorder. Gastrointestinal imaging and endoscopy is the diagnosis of the disease and the identification of mechanical obstruction an important method. In general, non-surgical treatment can be cured, changes in the mechanism of gastric emptying for the use of gastrointestinal motility drugs may receive better results