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目的研究女性月经期前后电阻抗乳腺扫描(EIS)检查图像的变化。方法 60例身体健康、25～45岁、不在孕期和哺乳期、未绝经的女性志愿者接受EIS。每人每周接受1次EIS常规检查,并且在每次月经周期前、后几天内也接受EIS检查,共持续14个月。观察月经期前后EIS成像的变化以及异常EIS成像与年龄的关系。统计分析采用配对卡方检验和卡方检验。结果观察发现异常亮斑(假阳性)在月经期前(月经期前3～5d)的EIS成像中出现,通常异常亮斑仅存在1周,到第3周(月经期后3～7d)后基本消失,并且成像结果更趋于均匀的灰度图。本组受试者中81.7%(49/60)的EIS成像在月经期前后发生变化。但也有18.3%(11/60)受试者的检查结果没有变化。60例受试者月经前3～5d与月经后4～7d的EIS检查成像比较差异有显著的统计学意义(P=0.000)。经期前、后EIS成像的变化与年龄无关(P>0.050)。结论女性月经前EIS成像可出现假阳性表现。为了能获得正确EIS检查结果建议进行EIS检测时应避开月经期前的时间段。
Objective To study the changes of electrical impedance mammography (EIS) before and after menstruation in women. Methods Sixty healthy women, 25-45 years old, not pregnant and lactating, were enrolled in this study. Each person receives a regular EIS routine examination once per week and also undergoes EIS examinations within a few days before and after each menstrual cycle for a total of 14 months. The changes of EIS imaging before and after menstruation and the relationship between abnormal EIS imaging and age were observed. Statistical analysis using paired chi-square test and chi-square test. RESULTS: Abnormal bright spots (false positives) were found in EIS imaging before menstruation (3 to 5 days before menstruation). Normal abnormal bright spots only existed for 1 week. By the 3rd week (3 ~ 7 days after menstruation) Basically disappear, and the imaging results tend to be more uniform grayscale. EIS imaging in 81.7% (49/60) of subjects in this group changed before and after menstruation. However, there were also 18.3% (11/60) subjects whose test results did not change. There were significant differences in EIS examination imaging between 3 ~ 5 days before menstruation and 4 ~ 7 days after menstruation in 60 subjects (P = 0.000). EIS imaging before and after menstruation had no relationship with age (P> 0.050). Conclusion Pre-menstrual EIS imaging may show false positives. In order to obtain the correct EIS test results, it is advisable to avoid the period before the menstrual period for EIS testing.