对77例有持续呼吸道症状(白日或夜间咳嗽、哮鸣及/或反复肺炎发作)、内科治疗无效的病人进行了食管测压和食管内pH的24小时监测,以了解有无隐性胃食管返流。食管测压时令病人吞咽10次以上,看食管有无运动异常(同时及/或重复收缩)。若20％以上的食管收缩异常,则食管有运动紊乱。食管的pH<4表示有返流。返流后3分钟内发生咳嗽、哮鸣者表示症状因吸入返流的胃酸而引起。咳嗽、哮鸣在返流前3分钟内发生者则表示返流因咳嗽、哮鸣时胸、腹部压力变化所引起。若咳嗽、哮鸣时pH>4,或在监测期内无咳嗽、哮鸣表示症状与返流无关,而是由于肺部原发 A total of 77 patients with persistent respiratory symptoms (daytime or nocturnal cough, wheezing and / or recurrent pneumonia episodes) and medical therapy were discontinued were monitored for esophageal manometry and esophageal pH for 24 hours to determine whether there was a recessive gastroesophageal Backflow. Esophageal manometry when the patient swallowed more than 10 times to see whether there is abnormal esophageal movement (and / or repeated contraction). If more than 20% of the esophageal anomalies, the esophageal motility disorders. Esophageal pH <4 indicates reflux. Cough occurs within 3 minutes after reflux and symptoms of the wheeze are caused by inhaled reflux of gastric acid. Cough, wheezing occurred within 3 minutes before the regurgitation said reflux due to cough, wheezing when the chest, abdominal pressure caused by changes. If cough, wheezing pH> 4, or no cough during the monitoring period, wheezing indicates that the symptoms have nothing to do with reflux, but due to the primary lung