论文部分内容阅读
本文对国产合成口服金剂KG881进行体内外免疫作用的实验研究,结果表明本品抑制正常小鼠、佐剂性关节炎大鼠脾脏T、B淋巴细胞增殖反应和腹腔巨噬细胞(PMφS)产生IL—1。并发现对正常小鼠体内NK活性无影响,但对体外NK活性呈抑制作用。综合提示本品具有显著的免疫抑制作用,活性与进口药金诺芬基本一致。
In this paper, domestic synthetic oral gold KG881 in vitro and in vivo experimental study showed that the product of normal mice, adjuvant arthritis in rats spleen T, B lymphocyte proliferation and peritoneal macrophage (PMφS) production IL-1. And found no effect on NK activity in normal mice, but in vitro inhibition of NK activity. Comprehensive tips This product has a significant immunosuppressive effect, activity and imported drugs Jinnuo Fen basically the same.