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本文报道经减敏、酮替芬及其他方法治疗的31例外源性哮喘病儿以及10名正常对照者,外周血淋巴细胞亚群的变化。结果。哮喘各组OKT_4,OKT_4/OKT3比值明显高于正常对照组P均<0.01)。OKT_3则相对增高,但与对照组相比,无统计学意义。经不同方法治疗后,OKT_4在减敏组较其他治疗组明显下降;OKT_3在各组间差异无显著性。结果表明:哮喘病儿存在着T细胞亚群功能紊乱,且减敏和酮替芬治疗对T细胞亚群功能的恢复均较其他治疗方法组为佳。
This article reports the changes of peripheral blood lymphocyte subsets in 31 extrinsic asthmatic children and 10 normal controls treated with desensitization, ketotifen and other methods. result. The ratio of OKT_4 and OKT_4 / OKT3 in asthmatic groups was significantly higher than that in normal control group (P <0.01). OKT_3 is relatively increased, but compared with the control group, no statistical significance. After treatment by different methods, OKT_4 in the desensitization group significantly decreased compared with other treatment groups; OKT_3 no significant difference between the groups. The results showed that there was dysfunction of T lymphocyte subsets in asthmatic children, and desensitization and ketotifen treatment were better than other treatment groups in the recovery of T cell subsets.