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目的：探讨黄芪注射液治疗肾综合征出血热（ＨＦＲＳ）的临床疗效。方法：１４６ 例ＨＦＲＳ患者随机分为２ 组，治疗组７６ 例，对照组７０ 例。２ 组患者均采用西医常规治疗，治疗组同时用黄芪注射液２０～３０ ｍ ｌ加入５％葡萄糖静滴，每日１ 次，疗程７～１０ 日。对照组则用病毒唑０．５～１．０ ｇ 加入５％ 葡萄糖或生理盐水２５０～５００ ｍ ｌ中静滴，每日１ 次，７日为１ 个疗程。结果：治疗组治愈率为９７．３７％ ，优于对照组９２．８６％ 。治疗组患者越低血压期、越少尿期和发热期直接进入多尿期者分别为６２ 例次、４４ 例次和３８ 例次，显著多于对照组（分别为４８ 例次、３１ 例次和２２ 例次），Ｐ均＜ ０．０１。治疗组尿素氮恢复正常时间和尿蛋白转阴时间〔（５．７０±０．９５）日和（５．０８±１．７９）日〕均较对照组〔分别为（８．３４±２．０６）日和（７．４３±２．５４）日〕显著缩短，Ｐ均＜ ０．０１。结论：黄芪注射液治疗ＨＦＲＳ可缩短病程，加速肾功能、尿蛋白恢复正常，且无不良反应。
Objective: To investigate the clinical efficacy of Astragalus injection in the treatment of hemorrhagic fever with renal syndrome (HFRS). Methods: A total of 146 patients with HFRS were randomly divided into two groups: 76 cases in the treatment group and 70 cases in the control group. The patients in both groups were treated by conventional western medicine. At the same time, the treatment group was treated with Astragalus Injection 20 ~ 30 ml by adding 5% glucose intravenously once daily for 7-10 days. The control group was treated with ribavirin 0.5 ~ 1.0g 5% glucose or saline 250 ~ 500ml intravenous infusion once daily, on the 7th for a course of treatment. Results: The cure rate of the treatment group was 97.37%, better than the control group 92.86%. In the treatment group, the lower the blood pressure period, the shorter the oliguria period and the fever period, the more directly into the polyuria period were 62 cases, 44 cases and 38 cases, respectively, significantly more than the control group (48 cases, 31 cases And 22 cases), P <0.01. In the treatment group, the recovery time of urea nitrogen and the time of urinary protein negative conversion were both (5.70 ± 0.95) days and (5.08 ± 1.79) days, respectively, compared with those in the control group (8.34 ± 2. 06) days and (7.43 ± 2.54) days〕 significantly shortened, P <0.01. Conclusion: Astragalus injection treatment of HFRS can shorten the course of disease, accelerate renal function, urinary protein returned to normal, and no adverse reactions.