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本文着重评价生物利用度方法的优缺点,以及分析在解释药物动力学数据时出现的最典型的误差。目前认为,对生物利用度的最合理定义为:药物的生物利用度即药物进入全身循环时的相对数量(全身吸收程度)和进入全身循环时的相
This article highlights the advantages and disadvantages of bioavailability methods and analyzes the most typical errors in interpreting pharmacokinetic data. At present, the most reasonable definition of bioavailability is as follows: the bioavailability of the drug is the relative amount of the drug entering the systemic circulation (the degree of systemic absorption) and the phase of entering the systemic circulation