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胰腺癌是目前预后最差的恶性肿瘤,早期诊断被认为是改善胰腺癌预后的重要出路之一.表面增强激光解吸电离飞行时间质谱(SELDI- TOF MS)技术,是近年来发展起来一种新的高通量蛋白质组学研究方法,本文就SELDI-TOF MS技术相关的原理、特点,在胰腺癌早期诊断中的应用新进展和未来的发展趋势作一综述.
Pancreatic cancer is the worst prognosis malignant tumor at present, and early diagnosis is considered as one of the important ways to improve the prognosis of pancreatic cancer.SELDI-TOF MS has developed in recent years High-throughput proteomics research methods, this article SELDI-TOF MS technology related to the principles and characteristics of the early diagnosis of pancreatic cancer in the application of new advances and future trends are reviewed.