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目的探讨三种不同方案在高龄妇女体外受精联合胚胎移植技术(IVF)助孕中的对比研究。方法 108例129个周期卵巢低反应患者,促排卵方案分成Ⅰ组(微量长方案)、Ⅱ组(拮抗剂方案)、Ⅲ组(微刺激方案),分析对比各组促排卵效果。结果 III组促性腺激素Gn天数、用量、HCG日LH值差异有统计学意义(P<0.05);其他各临床资料比较差异无统计学意义(P>0.05)。结论卵巢低反应患者实施微刺激方案效果更为明显,经济、临床价值更高。
Objective To investigate the comparative study of three different schemes in the assisted pregnancy of elderly women undergoing in vitro fertilization combined with embryo transfer (IVF). Methods One hundred and eighty patients with ovarian hyporesponse who had 129 cycles of ovarian failure were divided into group Ⅰ (minimal long term), group Ⅱ (antagonist) and group Ⅲ (slightly stimulated). The ovulation induction effects of each group were analyzed. Results There were significant differences in the days of gonadotrophin Gn, dosage, and HCG LH between the three groups (P <0.05). There was no significant difference in other clinical data (P> 0.05). Conclusions The patients with low response ovarian response to micro-stimulation effect is more obvious, economic, clinical value is higher.