Fas/FasL系统在介导细胞凋亡过程中起着重要的信号传递作用。在许多神经系统疾病中,凋亡在疾病的发生、发展中起重要作用,如在脑缺血、多发性硬化(MS)、阿尔茨海默病(AD)以及神经肌肉病中,均发现有Fas/FasL系统表达水平的变化,提示该系统可能参与了神经系统疾病的病理生理过程。 The Fas / FasL system plays an important signaling role in mediating apoptosis. In many diseases of the nervous system, apoptosis plays an important role in the occurrence and development of diseases such as cerebral ischemia, multiple sclerosis (MS), Alzheimer’s disease (AD) and neuromuscular diseases Fas / FasL system expression level changes, suggesting that the system may be involved in the pathophysiology of nervous system diseases.