The purpose of this paper is to discuss the poly-phase salt tectonics and its relation to the hydrocarbon accumulation of the Tarim superimposed basin. Several salt sequences are developed in the Tarim basin, they are: (1) the Mid-Early Cambrian salt sequence, mainly distributed in the west part of the north Tarim uplift and Keping uplift; (2) the Early Carboniferous salt sequence, mainly distributed in the south slope of the north Tarim uplift; (3) the Paleogene salt sequence, mainly distributed in the mid-west part of the Kuqa foreland fold belt and north Tarim uplift; and (4) the Miocene salt sequence, mainly distributed in the east part of the Kuqa foreland fold belt. The salt sequences deposited in the tectonically calm scenario, while the salt layers deformed during the period of intense tectonism. Although the salt sequences are characteristic of plastic flow, the differences of salt deformation styles exist in the different salt sequences because of the different deformation mechanism. It is attractive that the distribution of the large oil-gas fields or pools has a bearing upon the salt sequences and salt structures, such as the Tahe oilfield related to the Lower Carboniferous salt sequence and laterally facies changed mudstone, the Kela No.2 gas field to the Paleogene salt structures, and the Dina gas field to the Miocene salt structures. It is indicated that the large-scale hydrocarbon accumulation is controlled by the poly-phase salt sequences and structures. The deep analysis of the poly-phase salt tectonics is helpful to understanding the characteristics of the structural deformation and oil-gas accumulation of the Tarim basin.