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同时应用环胞菌素 A( C S A),抗胸腺细胞球蛋白( A T G),大剂量免疫球蛋白( H D I G)和大剂量甲基泼尼松龙( H D M P)等免疫抑制剂对 17 例小儿 S A A(10 例 S A AⅠ,7 例 S A AⅡ)进行联合免疫抑制( I S)治疗。结果 3 例基本治愈,7例缓解,3 例明显进步,总有效率达 76.5% (13/17 例)。其中 10 例 S A AⅠ的总有效率为 80% 。在总共 13 例有效病例中,大部分(10/13 例,76.9% )为缓解或基本治愈,故有效率及显效质量均明显高于近年来单药治疗 S A A 的报道,联合 I S治疗期间未见明显感染倾向加重或脏器功能损害。
Simultaneous application of cyclosporin A (C S A), anti-thymocyte globulin (A T G), high-dose immunoglobulin (H D I G) and high-dose methylprednisolone (H D M P) And other immunosuppressive agents on 17 cases of pediatric SA (10 cases of SA A Ⅰ, 7 cases of SA A Ⅱ) combined immunosuppression (I S) treatment. Results Three cases were basically cured, seven cases were relieved and three cases were markedly improved. The total effective rate was 76.5% (13/17 cases). Of which 10 cases of SA A Ⅰ total efficiency of 80%. In a total of 13 effective cases, the majority (10/13 cases, 76.9%) were relieved or basically cured, so the effective and effective quality were significantly higher than those reported in recent years, monotherapy SA S no significant infection during treatment or exacerbated organ damage.