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目的：观察他莫昔芬治疗乳腺囊性增生病的效果。方法：用周期性给药法，即月经后ｄ２，给他莫昔芬１０ｍｇ，ｐｏ，ｂｉｄ，至下次月经来潮时停药，为一个疗程，每个疗程停药３～５ｄ，全部病例均经２个以上疗程的治疗。结果：显效１０１例（８４．１％），有效１４例（１１．７％），无效５例（４．２％），总有效率９５．８％，随访３２例，复发３例（９％），治疗中仅６例（５％）出现月经紊乱，经量增多或减少，停药后自愈。结论：他莫昔芬月经周期给药法为治疗乳腺囊性增生病开辟了一个新的途径，值得推广。
Objective: To observe the effect of tamoxifen on cystic hyperplasia of the breast. Methods: With periodic administration, that is, after menstruation d2, tamoxifen 10mg, po, bid, until the next menstrual cramps when withdrawal, for a course of treatment, each course of treatment for 3 ~ 5d, all cases were After more than 2 courses of treatment. Results: The effective rate was 101 cases (84.1%), effective rate was 14 (11.7%), effective rate was 5 (4.2%), the total effective rate was 95.8% ), Only 6 cases (5%) had menstrual disorders during the treatment, with the increase or decrease in the amount of the menstrual cramps, self-healing after stopping the treatment. Conclusion: Tamoxifen menstrual cycle method for the treatment of cystic hyperplasia of breast opened up a new way, it is worth promoting.