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鉴于恶性疟时,脑型疟的发病率和死亡率都很高,研究其恶化的原因已成为重要课题。为了探讨影响脑型疟预后的原因,作者在尼日利亚对1987～1989年因脑型疟入院治疗的儿童病例进行了观察。病儿的年龄为1.2～13岁,平均年龄5.7±3.2岁。其中男性32例,女性29例。入院时这些病儿均处于昏迷状态,病人的昏迷程度按改良的Glasgow等级划分。每例病儿均用氯喹治疗,并记录体温、脉搏、血压、呼吸、昏迷的程度、昏迷恢复时间、原虫清除时间、退热时间等。对死亡病例进行尸检,包括脑组织的病理组织学观察。结果在观察的61例患者中,有50例恢复,11例死亡。5例昏迷Ⅱ级的病儿全
Given the high incidence and mortality of cerebral malaria when falciparum malaria is present, studying the causes of its deterioration has become an important issue. In order to investigate the reasons for the prognosis of cerebral malaria, the author observed the cases of children hospitalized with cerebral malaria from 1987 to 1989 in Nigeria. The sick child’s age is 1.2 to 13 years old, with an average age of 5.7 ± 3.2 years. There were 32 males and 29 females. These sick children were in a coma at admission, and the patient’s coma was divided by a modified Glasgow rating. Each patient was treated with chloroquine, and recorded temperature, pulse, blood pressure, respiration, coma degree, coma recovery time, protozoal clearance time, antipyretic time. Autopsy of death cases, including histopathological observation of brain tissue. Results Of the 61 patients observed, 50 recovered and 11 died. 5 cases of coma Ⅱ grade sick children