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目的:分析头孢曲松钠所致泌尿系结石不良反应的特点及相关因素,为临床合理用药提供参考。方法:对国内外发表的使用头孢曲松钠出现的泌尿系结石不良反应报道进行统计和分析。结果:检索到头孢曲松钠引起的泌尿系结石不良反应39例。不良反应的发生,以男性婴幼儿患者应用头孢曲松钠诱发的泌尿系结石数量较多,应引起重视。头孢曲松钠致泌尿系结石在B超和膀胱镜下均有表现,停药后对症治疗,结石多数自行消失。结论:临床应重视头孢曲松钠的泌尿系结石不良反应,用药时注意患者的临床表现。
OBJECTIVE: To analyze the characteristics and related factors of adverse reactions of urinary calculi caused by ceftriaxone sodium, and to provide a reference for clinical rational drug use. Methods: The reports of adverse reactions of urinary calculus using ceftriaxone sodium published at home and abroad were analyzed and statistically analyzed. Results: 39 cases of adverse reactions of urinary calculi caused by ceftriaxone were retrieved. Adverse reactions occurred in male infants with ceftriaxone induced urinary tract stones more than the number should be taken seriously. Ceftriaxone sodium-induced urinary calculi in the B-and cystoscopy have performance, symptomatic treatment after stopping, most of the stones disappear on their own. Conclusion: Clinically, attention should be paid to the adverse reactions of ceftriaxone sodium in urolithiasis. Pay attention to the clinical manifestations of the patients when using it.