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目的探讨新生儿先天性心脏病发病因素,为预防及早期诊疗提供依据。方法回顾性分析我科2005-2010年住院的92例确诊为先天性心脏病新生儿临床资料的诊断方法和病因、诱因。结果左向右分流(非青紫型)34例,右向左分流(青紫型)15例,无分流型43例。母孕早期感染后服药52例,未正规服用叶酸33例,孕期接触计算机10例,孕期常使用手机57例,父亲喝酒73例,父亲抽烟75例,家族中有先心病者8例,患有21-体综合征1例。结论新生儿先心病主要临床表现为青紫,呼吸困难,心衰,体质量不增,心脏杂音。孕期环境和遗传等高危因素对先天性心脏病发生影响明显,患先天性心脏病的危险性高。
Objective To explore the pathogenesis of neonatal congenital heart disease and provide evidence for prevention and early diagnosis and treatment. Methods Retrospective analysis of 92 cases diagnosed as neonatal congenital heart disease in our department from 2005 to 2010 were retrospectively analyzed. Results Left to right shunt (non-purple type) 34 cases, right to left shunt (purple type) 15 cases, no shunt 43 cases. In the first trimester of pregnancy, 52 cases took medicine after taking the first infection, 33 cases did not take folic acid formally, 10 cases came into contact with the computer during pregnancy, 57 cases were using mobile phone during pregnancy, 73 were dad drinking, 75 were dad smoking, 8 were family members with congenital heart disease, 21-body syndrome in 1 case. Conclusion The main clinical manifestations of neonatal CHD are bruising, dyspnea, heart failure, body mass gain and heart murmur. High risk factors such as pregnancy environment and genetics have a significant impact on congenital heart disease, high risk of congenital heart disease.