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目的 了解新生儿缺氧缺血性脑病 (HIE)患儿 1～ 3年的预后。 方法 对存活出院的15 7例 HIE患儿定期随访 ,采用 Gesell智能初评法、体格发育及 Vojta七种姿势检查 ,综合评估预后。结果 12 9例康复。2 8例异常 ,其中 7例仅表现为轻度智力低下 ,脑电图及 Vojta检查在正常范围。2 1例有明显神经系统后遗症 ,其中脑性瘫痪 16例 ,婴儿痉挛症 5例 ,后遗症发生率为 13.4%。 结论 新生儿 HIE可致神经系统后遗症 ,其预后的好坏与急性期临床分型及神经系统症状的严重程度、持续时间密切相关。综合多项临床资料可相对准确地预测预后。
Objective To understand the prognosis of neonates with hypoxic-ischemic encephalopathy (HIE) 1-3 years. Methods A total of 15 7 HIE patients discharged from hospital were followed up regularly. Gesell’s intelligence initial assessment, physical development and Vojta posture examination were used to evaluate the prognosis. Results 12 9 cases of rehabilitation. There were 28 cases of abnormalities, of which 7 cases showed only mild mental retardation, EEG and Vojta examination were in the normal range. There were obvious neurological sequelae in 21 cases, including 16 cases of cerebral palsy, 5 cases of infantile spasms, and the incidence of sequelae was 13.4%. Conclusions Neonatal HIE can cause neurological sequelae. The prognosis of HIE is closely related to the clinical classification of acute phase and the severity and duration of neurological symptoms. Comprehensive clinical data can be relatively accurate prognosis.