欧洲白蜡树、毛果一支黄花和白杨等很早以来就在民间作为药用。80年代,德国 Steiger—wald Arzneimittelwerk 公司将上述3种植物的提取物开发成了抗炎、抗风湿的复方制剂菲托道洛并用于临床。本文综述了这3种植物的提取物及菲托道洛的化学成分和药理活性,表明菲托道洛不但具有与合成的非甾体抗炎药相同的功效,而且副作用较少。 The European ash tree, a yellow flower of Maoguo, and poplar have been used medicinally for a long time. In the 1980s, Germany’s Steiger-wald Arzneimittelwerk developed the extracts of the above-mentioned three plants into the anti-inflammatory and anti-rheumatic compound phentol, which was used clinically. This article reviews the chemical composition and pharmacological activity of the extracts of these three plants and phenothazone, indicating that tigtrolone not only has the same efficacy as synthetic non-steroidal anti-inflammatory drugs, but also has fewer side effects.