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甲氰咪胍(cimetidine)系一种有效的H_2受体拮抗剂,抑制基础胃酸的分泌,阻断组胺、喂食、咖啡因、低血糖和胃泌素等刺激胃酸分泌的反应。临床试用的结果,此药可促进十二指肠溃疡愈合、改善Zollinger-Ellison综合征的症状和使溃疡愈合。对酸性反流性食管炎、胃溃疡、胃粘膜糜烂亦可能有效。有助于减少十二指肠溃疡复发,加强在胰功能不足的病人中应用胰酶替代疗法的疗效。此药在临床上已广
Cimetidine is a potent H 2 receptor antagonist that inhibits the secretion of basal gastric acid, blocking histamine, feeding, caffeine, hypoglycemia, and gastrin to stimulate gastric acid secretion. As a result of clinical trials, this medicine can promote the healing of duodenal ulcers, improve the symptoms of Zollinger-Ellison syndrome and heal ulcers. Acid reflux esophagitis, gastric ulcer, gastric mucosal erosion may also be effective. Help to reduce the recurrence of duodenal ulcer and strengthen the therapeutic effect of pancreatic enzyme replacement therapy in patients with pancreatic insufficiency. This medicine is already clinically widespread