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目的：分析SNIP中PCNA与Bcl-2的表达与意义。方法对所有蜡块进行切片处理，切片的厚度为5μm，同时使用PV法进行化学染色。结果所有切片均存在Bcl-2及PCNA阳性表达，阳性Bcl-2表达主要集中于细胞膜及细胞浆，而阳性PCNA表达则集中于细胞核当中。结论细胞增殖与凋亡抑制过程同时存在于SNIP发展及恶化进程中，凋亡抑制过程与增殖过程相互促进，增殖加速时，凋亡也在加快。“,”objective to analyze the expression of PCNA and Bcl - 2 “with meaning. Carried out on al the wax block slice processing, the thickness of the slice is 5 microns, while using PV method for chemical staining. Results al exist the Bcl - 2 slices and PCNA positive expression, positive Bcl - 2 expression mainly focused on the cellmembrane and cytoplasm, and positive expression of PCNA is concentrated in the nucleus. Conclusions cellproliferation and apoptosis inhibition process exists in ”at the same time in the process of development and progression, apoptosis and proliferation inhibition process promote each other, accelerated proliferation apoptosis is accelerated.