家族性食管癌与遗传的关系目前尚无定论,本文报告二家系连续3代共8人罹病。先证者 (Ⅱ_5)男,51岁。1982年X线片诊断为上段食管癌,病理为鳞状癌。患者生于山西省襄垣县,16岁离晋,32岁定居淮南,53岁死于食道癌肺转移。家族史;Ⅰ_1(Ⅱ_5之父)世居原籍,务农,71岁死于 The relationship between familial esophageal cancer and inheritance is inconclusive at present, this article reports two families of 3 consecutive generations of 8 people suffering from disease. The proband (Ⅱ_5) male, 51 years old. In 1982 the upper X-ray diagnosis of esophageal cancer, pathological squamous cancer. The patient was born in Xiangyuan County, Shanxi Province, leaving Jin at the age of 16, settling in Huainan at the age of 32 and died of lung metastasis at the age of 53 from the esophagus. Family history; Ⅰ_1 (father of Ⅱ_5) native place, farming, died at age 71