川芎嗪即四甲基吡嗪(Tetramethyl pyrazine)系北京制药工业研究所在研究中药川芎有效成分时所创制的新药。临床上静脉给药对缺血性脑血管病等有较好的.疗效。近年来,在心肌药理动力学和电生理特性的研究中,发现它是一种新型的“钙离子拮抗剂,,,因此,我们对该品的不同剂型进行了生物利用度和药物动力学 Tetramethylpyrazine (tetramethylpyrazine) is a new drug developed by Beijing Institute of Pharmaceutical Industry when studying the active ingredients of Chuanxiong. Clinical intravenous administration of ischemic cerebrovascular disease have better curative effect. In recent years, it has been found that it is a new type of ”calcium antagonist" in the study of cardiomyocyte pharmacokinetics and electrophysiological properties. Therefore, we conducted bioavailability and pharmacokinetics on different dosage forms of this product