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热塑型橡胶(Thermoplastic Rubber),简称TPR,俗称人造橡胶。本实验采用SBS、抗氧化剂1010、液体石蜡(15#)、145树脂等为原料配制TPR凝胶,用直接混合法制备了含樟脑的TPR凝胶贴剂,并经乙醇浸出后用GC检测了樟脑含量。实验结果表明:TPR凝胶可作为挥发油类药物贮库,其内含的挥发油成分可在乙醇中释放,其释放量与时间有明显相关性。本实验具有一定的理论和实用价值,为TPR凝胶作为外用贴敷类药物载体的应用做了探索性工作。
Thermoplastic rubber (Thermoplastic Rubber), referred to as TPR, commonly known as artificial rubber. In this experiment, TPR gel was prepared by using SBS, antioxidant 1010, liquid paraffin (15 #), 145 resin as raw materials, and the TPR gel containing camphor was prepared by direct mixing method and detected by GC after ethanol leaching Camphor content. The experimental results show that TPR gel can be used as a volatile oil drug depot, the volatile oil components contained in it can be released in ethanol, and the release amount is obviously correlated with time. This experiment has a certain theoretical and practical value, as TPR gel as a topical application of drug carrier application made a exploratory work.