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目的探讨影响同时性结直肠癌肝转移同期肝切除预后的因素。方法回顾性分析1994年8月至2004年12月在中山大学附属第一医院胃肠外科行肝肠同期切除的39例同时性结直肠癌肝转移病人临床资料,选择相关临床因素进行预后分析。结果所有病人术后5年存活率为14.3%,单因素分析显示病人年龄<70岁、肝转移瘤切缘距离≥1cm是影响同期肝切除术后生存率的因素,Cox多因素回归分析显示术后生存时间仅与肝转移瘤切缘距离≥1cm显著相关(P<0.05)。结论肝转移瘤切缘距离是影响同时性结直肠癌肝转移同期肝切除预后的独立因素,肝转移瘤切除应力争切缘距离≥1cm。
Objective To explore the factors influencing the prognosis of simultaneous hepatic resection of colorectal cancer with liver metastases. Methods The clinical data of 39 patients with concurrent liver metastasis of colorectal cancer who underwent simultaneous resection of enterohepatic gastrectomy in the First Affiliated Hospital of Sun Yat-sen University from August 1994 to December 2004 were analyzed retrospectively. Results The 5-year survival rate of all patients was 14.3%. Univariate analysis showed that the age of the patients was less than 70 years and the margin of the liver metastases was more than 1 cm, which was the factor influencing the survival rate after hepatectomy. Cox regression analysis showed that Post-survival time was only significantly associated with the margin of hepatic metastases ≥1 cm (P <0.05). Conclusion The resection margin of hepatic metastases is an independent factor affecting the prognosis of concurrent liver resection with concurrent resection of liver metastases.