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目的:了解儿童中度铅中毒临床特点及依地酸二钠钙驱铅治疗、营养干预治疗的疗效及安全性。方法:回顾性分析我院收治的两起铅冶炼厂污染环境事件中的儿童中度铅中毒病例,对其临床特点、治疗效果及安全性进行分析总结。结果:儿童中度铅中毒的患儿中男性占61.32%,1～6岁儿童占66.04%;儿童铅中毒临床表现无特异性,42.45%的患儿无明显临床表现;治疗后血铅明显降低,营养干预加驱铅治疗组血铅下降幅度大于单纯营养干预组;治疗过程中无一例出现并发症。结论:营养干预、驱铅治疗疗效好、安全性高,且营养干预加驱铅治疗效果明显优于单纯营养干预。
Objective: To understand the clinical features of children with moderate lead poisoning and edetate disodium calcium lead treatment, nutritional intervention treatment efficacy and safety. Methods: A retrospective analysis of two lead smelters contaminated environmental accidents in our hospital children with moderate lead poisoning cases, the clinical features, treatment and safety analysis. Results: Among children with moderate lead poisoning, 61.32% were male, 66.04% were children aged 1-6, children had no specific clinical manifestations of lead poisoning, 42.45% had no clinical manifestations, and blood lead levels were significantly lower after treatment , Nutritional intervention plus lead-induced blood lead levels decreased more than simple nutrition intervention group; no complications occurred during the treatment. Conclusion: Nutritional interventions and lead-removing therapy have good curative effect and high safety. Nutritional intervention plus lead-removing therapy is obviously better than simple nutrition intervention.