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目的:观察呼吸科住院病人肺炎衣原体感染状况。方法:采用间接免疫荧光滴定平板技术和微量免疫荧光试验检测65例呼吸科住院患者(病例组)和67名同期健康献血员(对照组)的肺炎衣原体特异性IgA、IgG、IgM抗体。结果:病例组中,41例(63%)患者的IgA抗体水平升高,其中肺癌占26例,COPD并肺部感染13例;与正常对照组6例(9%)比较,差异具有统计学意义(P<0.001)。既往感染率两组比较差异无统计学意义。结论:肺炎衣原体是呼吸科住院病人的重要致病菌之一,以肺癌与COPD患者居多。
Objective: To observe the status of Chlamydia pneumoniae inpatients in respiratory department. Methods: Chlamydia pneumoniae specific IgA, IgG and IgM antibodies were detected by indirect immunofluorescence titration and microimmunofluorescence assay in 65 inpatients with respiratory diseases (case group) and 67 healthy blood donors (control group). Results: In the case group, IgA antibody levels increased in 41 patients (63%), including 26 cases of lung cancer and 13 cases of COPD and pulmonary infection. Compared with 6 cases (9%) of the normal control group, the difference was statistically significant Significance (P <0.001). Previous infection rate was no significant difference between the two groups. Conclusion: Chlamydia pneumoniae is one of the most important pathogenic bacteria in respiratory patients inpatients, with lung cancer and COPD patients mostly.