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目的:对426例眼部肿瘤进行病理分析。方法:复习我院病理科1982～1997年间所检查的457例眼科病理资料,对其中的426例眼部肿瘤进行分析。结果:良性肿瘤290例（68.1％）,恶性肿瘤136例（31.9％）。按发病解剖学部位分类:眼睑肿瘤272例（63.8％）,角结膜肿瘤44例（10.3％）,视网膜肿瘤34例（8％）,眼眶肿瘤76例（17.8％）。按组织学分类,眼睑良性肿瘤前5位为色素痣83例,各种囊肿39例,基底细胞乳头状瘤34例,鳞状上皮乳头状瘤17例,脉管瘤14例。眼睑恶性肿瘤为:基底细胞癌33例,鳞状细胞癌16例,睑板腺癌10例,恶性黑色素瘤7例。角结膜肿瘤较少。视网膜肿瘤34例,全部为视网膜母细胞瘤。眼眶良性肿瘤前5位为:各种上皮性囊肿17例,神经纤维瘤10例,泪腺混合瘤10例,炎性假瘤9例,血管瘤5例。眼眶恶性肿瘤以鳞状细胞癌10例占首位,其余依次为泪腺混合瘤恶变4例、基底细胞癌2例,间叶组织来源的血管肉瘤、平滑肌肉瘤、横纹肌肉瘤各1例。
Objective: To analyze the pathology of 426 cases of ocular tumors. Methods: 457 cases of ophthalmic and pathological data examined in our hospital from 1982 to 1997 were reviewed, of which 426 cases of ocular tumors were analyzed. Results: There were 290 benign tumors (68.1%) and 136 malignant tumors (31.9%). According to the anatomic site of pathogenesis, 272 cases (63.8%) of eyelid tumors, 44 cases (10.3%) of conjunctival tumors, 34 cases (8%) of retina tumors and 76 cases (17.8%) of orbital tumors. According to histological classification, the top 5 eyelid benign tumors were nevus of 83 cases, all kinds of cysts in 39 cases, basal cell papilloma in 34 cases, squamous epithelial papilloma in 17 cases, and vascular tumor in 14 cases. Eyelid malignant tumors: basal cell carcinoma in 33 cases, squamous cell carcinoma in 16 cases, meibomian gland carcinoma in 10 cases, 7 cases of malignant melanoma. Less conjunctival tumors. Retinal tumors in 34 cases, all of retinoblastoma. The first 5 benign orbital tumors were as follows: 17 cases of various epithelial cysts, 10 cases of neurofibroma, 10 cases of mixed lacrimal gland tumor, 9 inflammatory pseudotumor and 5 hemangiomas. Orbital malignant tumors accounted for 10 cases of squamous cell carcinoma in the first place, followed by malignant transformation of the lacrimal gland in 4 cases, basal cell carcinoma in 2 cases, mesenchymal sarcoma, leiomyosarcoma, rhabdomyosarcoma in 1 case.