论文部分内容阅读
目的探讨沙培林配合化疗治疗晚期非小细胞肺癌(NSCLC)的疗效。方法将46例晚期NSCLC患者分为两组,治疗组26例,对照组20例。治疗组采用沙培林配合NP方案化疗,对照组单纯用NP方案化疗。结果治疗组总有效率(CR+PR)为50.0%(13/26),对照组(CR+PR)45.0%(9/20)。治疗组达到有效所用时间平均为40 d,对照组84 d。治疗组白细胞下降和脱发等不良反应均比对照组明显减轻。结论沙培林和NP方案化疗治疗NSCLC疗效好,达到有效所用时间短,不良反应小。
Objective To investigate the efficacy of saperolin in combination with chemotherapy in the treatment of advanced non-small cell lung cancer (NSCLC). Methods Forty-six patients with advanced NSCLC were divided into two groups: treatment group (26 cases) and control group (20 cases). The treatment group with shaplex with NP regimen chemotherapy, the control group simply with NP regimen. Results The total effective rate (CR + PR) was 50.0% (13/26) in the treatment group and 45.0% (9/20) in the control group (CR + PR). The mean effective time for the treatment group was 40 days and that of the control group 84 days. Treatment group leukopenia and hair loss and other adverse reactions were significantly reduced compared with the control group. Conclusion Sapirin and NP regimens have a good curative effect in treating NSCLC with short effective time and little adverse reactions.