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目的探讨癌胚抗原(CEA)、肿瘤相关物质(TSGF)、LP(a)联合检测对肺癌的意义。方法测定82例肺癌患者的CEA、LP(a)及TSGF水平的变化,并和健康对照组,肺炎组比较。结果肺癌组CEA、LP(a)、TSGF的水平明显高于对照组(P<0.01),肺支气管炎组LP(a)的水平明显比肺癌组高(P<0.05)。三者联合检测准确性、敏感性、特异性均有提高。结论联合检测患者血清LP(a)、CEA、TS-GF对肺癌的诊断具有重要临床意义;血清LP(a)虽不能作为肺癌的筛选指标,但肺部有病变患者LP(a)水平很高,可提示存在肺癌可能性。
Objective To investigate the significance of combined detection of carcinoembryonic antigen (CEA), tumor related substances (TSGF) and LP (a) in lung cancer. Methods The levels of CEA, LP (a) and TSGF in 82 patients with lung cancer were measured and compared with healthy controls and pneumonia group. Results The levels of CEA, LP (a) and TSGF in lung cancer group were significantly higher than those in control group (P <0.01). The level of LP (a) in lung bronchitis group was significantly higher than that in lung cancer group (P <0.05). The three joint detection accuracy, sensitivity, specificity have increased. Conclusions Serum LP (a), CEA and TS-GF in patients with lung cancer have important clinical significance in the diagnosis of lung cancer. Serum LP (a) may not be used as a screening index for lung cancer, but LP (a) , May prompt the possibility of lung cancer.