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本文综述了血管内皮生长因子(VEGF)的基因结构、生物学特性和功能,探讨了VEGF在肿瘤中的表达及调控机制,VEGF与肿瘤血管形成以及VEGF与肿瘤抗血管生成治疗。探讨血管再生与肿瘤的关系是目前肿瘤生物学研究中相当热门的课题。VEGF已经成为治疗肿瘤的新的靶点。随着肿瘤血管生成?
This review summarizes the gene structure, biological characteristics and functions of vascular endothelial growth factor (VEGF), discusses the expression and regulation of VEGF in tumors, VEGF and tumor angiogenesis, and VEGF and tumor antiangiogenic therapy. To explore the relationship between angiogenesis and tumor is a very hot topic in the study of tumor biology. VEGF has become a new target for the treatment of tumors. With tumor angiogenesis?