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目的 :探讨抗心肌肌球蛋白抗体对小儿心脏病的诊断价值。方法 :运用酶联免疫吸附法检测了 3 0例病毒性心肌炎 (VMC)、 14例扩张型心肌病 (DCM)、 10例风湿性心脏病 (RHD)、 2 2例先天性心脏病 (CHD)患儿血浆抗肌球蛋白抗体水平。结果 :抗肌球蛋白抗体在VMC和DCM患儿中的阳性率显著高于RHD、CHD和NC三组研究对象 (P均 <0 . 0 5 )。抗肌球蛋白抗体诊断VMC和DCM的敏感性为 5 4 5 5 % ,特异性为 89 47%。结论 :抗肌球蛋白抗体可作为小儿VMC和DCM的特异性诊断指标 ,有推广到基层医院的实用价值
Objective: To investigate the diagnostic value of anti-myocardial myosin antibody in children with heart disease. Methods: 30 cases of viral myocarditis (VMC), 14 cases of dilated cardiomyopathy (DCM), 10 cases of rheumatic heart disease (RHD) and 22 cases of congenital heart disease (CHD) were detected by enzyme linked immunosorbent assay Children with plasma anti-myosin antibody levels. Results: The positive rates of anti-myosin antibody in VMC and DCM were significantly higher than those in RHD, CHD and NC (all P <0.05). Anti-myosin antibodies to VMC and DCM sensitivity of 545%, specificity of 89 47%. Conclusion: Anti-myosin antibody can be used as a specific diagnostic indicator of pediatric VMC and DCM, which has the practical value of promoting to the primary hospital