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5例终末期酒精性肝硬变病人在香港大学玛丽医院肝胆外科施行原位肝移植手术。男4例,女1例。年龄41~55岁,平均468岁。病人均经心理医学医生评估适合作肝移植,并且在肝移植前至少戒酒6个月。供肝全部来自脑干死亡病人。供肝灌注和保存应用UW液。4例肝移植术中应用静脉转流技术,1例采用Piggyback法。术后应用类固醇、硫唑嘌呤和环胞霉素A作免疫抑制治疗。移植肝脏和患者的存活率均为100%,并已分别生存6月~3年,情况良好。肝移植可使末期酒精性肝硬变病人延长生命和恢复正常生活。
Five patients with end-stage alcoholic cirrhosis underwent orthotopic liver transplantation at the Hepatobiliary Surgery Center, Queen Mary Hospital, Hong Kong University. 4 males and 1 female. Aged 41-55 years old, with an average of 46.8 years old. All patients were evaluated by a psychiatrist for liver transplantation and abstained from alcohol for at least 6 months prior to liver transplantation. Liver from the brainstem all the patients died. Liver perfusion and preservation application UW solution. 4 cases of liver transplantation using venous bypass technology, 1 case using Piggyback method. Postoperative steroids, azathioprine and cyclosporine A were used as immunosuppressive therapy. Liver and patient survival rates were 100%, and have been living in June to 3 years, in good condition. Liver transplantation can prolong life and return to normal life in patients with terminal alcoholic cirrhosis.