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山梨醇是甘露醇的同分异构体,其作用机制和渗透压与甘露醇相似。静脉注射山梨醇高渗水溶液,可引起溶质性的利尿作用,提高血液渗透压,使周围组织和脑实质脱水,从而减轻顱内压和清除组织水肿。文献报道,静脉注射山梨醇50%或25%的高渗水溶液(按每公斤体重1～2克/日计算),可用于抢救脑外伤,防治青光
Sorbitol is an isomer of mannitol, its mechanism of action and osmotic pressure similar to mannitol. Intravenous injection of sorbitol hypertonic aqueous solution, can cause solute diuretic effect, increase blood osmotic pressure, so that the surrounding tissue and brain parenchyma dehydration, thereby reducing intracranial pressure and tissue edema. Reported in the literature, intravenous injection of sorbitol 50% or 25% of the hypertonic solution (per kg of body weight 1 to 2 grams / day basis), can be used to rescue traumatic brain injury, prevention and treatment of glaucoma