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本文从HLaEDTA·7H_2O和出发制得了标题化合物,研究了它的差热-热重、摩尔电导、紫外光谱、红外光谱及质子核磁共振谱等性质。从水溶液中培养出了该配合物的单晶体,用X射线衍射法测定了它的晶体及分子结构。晶体属单斜晶系,空间群P2_1/n。晶胞参数:a=14.735(2),b=29.335(3),c=16.409(2),β=99.24(3),Z=4,d_(cal)=1.665g/cm~3。结果表明:La~(3+)与EDTA~(4-)的配合阴离子具有二聚体形式。EDTA~(4-)以六齿中的五个齿与一个La~(3+)配位,而第六齿——羧基上一个氧同时向两个La~(3+)配位,形成了一个平行四边形[La_2O_2]双金属核结构。每个La~(3+)上还有两个水分子配位。缔合阳离子是两个3,6-双-(二甲氨基)-二苯并碘杂-2,5-环己二烯。该配合物对白血病L7712癌细胞显示出明显的抑制作用。
In this paper, the title compound was prepared by starting with HLaEDTA · 7H2O and its properties of differential thermal-thermogravimetry, molar conductivity, ultraviolet spectrum, infrared spectrum and proton nuclear magnetic resonance were studied. Single crystal of the complex was grown from aqueous solution and its crystal and molecular structure were determined by X-ray diffraction. The crystal is monoclinic, space group P2_1 / n. Cell parameters: a = 14.735 (2), b = 29.335 (3), c = 16.409 (2), β = 99.24 (3), Z = 4 and d cal = 1.665 g / cm 3. The results show that the anions of La ~ (3+) and EDTA ~ (4-) have dimers. EDTA ~ (4-) coordinates one La ~ (3+) with five teeth of six teeth and one oxygen of the sixth tooth-carboxyl group coordinates with two La ~ (3+) simultaneously to form A parallelogram [La_2O_2] bimetallic core structure. Each La ~ (3 +) there are two water molecules coordination. The associated cation is two 3,6-bis- (dimethylamino) -dibenzocho-2,5-cyclohexadiene. The complex showed a significant inhibitory effect on leukemia L7712 cancer cells.