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目的观察苯磺酸左旋氨氯地平(施慧达)对高血压病患者颈动脉内膜中层厚度(CIMT)及心脏质量指数(LVMI)的影响,从而评价苯磺酸左旋氨氯地平(施慧达)治疗高血压病的疗效。方法选取100例高血压病患者,给予苯磺酸左旋氨氯地平(施慧达)治疗12个月。用药前、用药12个月后测定颈动脉内膜中层厚度(CIMT)及心脏质量指数(LVMI),将用药前后数据进行比较,以了解苯磺酸左旋氨氯地平(施慧达)对颈动脉内膜中层厚度(CIMT)及心脏质量指数(LVMI)的影响。结果患者经治疗后血压显著低于治疗前血压,差异有统计学意义(P<0.01),血压控制率为92.6%;治疗后颈动脉内膜中层厚度(CIMT)及心脏质量指数(LVMI)明显低于治疗前,差异有统计学意义(P<0.05)。结论苯磺酸左旋氨氯地平(施慧达)降压效果良好,还能有效逆转颈动脉内膜中层厚度(CIMT)及降低心脏质量指数(LVMI)。
Objective To observe the effect of levamlodipine besylate on carotid artery intima-media thickness (CIMT) and heart mass index (LVMI) in patients with essential hypertension, so as to evaluate the effect of levamlodipine besylate Efficacy of blood pressure. Methods 100 cases of hypertensive patients were selected levamlodipine besylate (Shi Huida) for 12 months. Before treatment, carotid intima-media thickness (CIMT) and cardiac mass index (LVMI) were measured after 12 months of treatment. The data before and after treatment were compared to understand the effects of levamlodipine besylate on the carotid intima Middle thickness (CIMT) and heart mass index (LVMI). Results The blood pressure after treatment was significantly lower than that before treatment (P <0.01), and the rate of blood pressure control was 92.6%. The carotid artery intima-media thickness (CIMT) and cardiac mass index (LVMI) Before treatment, the difference was statistically significant (P <0.05). Conclusion Levamlodipine besylate has a good antihypertensive effect and can effectively reverse the carotid intima-media thickness (CIMT) and reduce the heart mass index (LVMI).