1概述骨髓基质干细胞(BMSCs),是骨髓基质中可在特定条件下分化为多胚层起源组织的非造血干细胞。大量实验证明BM-SCs具有多向分化潜能[1],研究表明骨髓基质干细胞向成骨细胞的转化首先是转化为骨祖细胞,后最终分化为成骨细胞和骨细胞,即使在体外脱离诱导物培养条件下也能成骨[2 1 Overview Bone marrow stromal stem cells (BMSCs) are non-hematopoietic stem cells that can differentiate into the tissue of origin of the mesoderm under certain conditions in the bone marrow stroma. A large number of experiments have shown that BM-SCs have a multi-directional differentiation potential [1], studies have shown that the conversion of bone marrow stromal cells to osteoblasts first transformed into osteoprogenitors, eventually differentiated into osteoblasts and osteocytes, even in vitro induction Material culture conditions can also be osteogenesis [2