内皮祖细胞(endothelial progenitor cell,EPC)是一类最初产生于骨髓,并能定向分化为成熟血管内皮细胞的前体细胞,参与血管新生,并在血管内皮修复及维持血管内皮组织自身平衡中起关键作用。从骨髓刺激内皮祖细胞的动员,增加循环内皮祖细胞的数量,是促进血管新生及内皮修复的一种有效措施。本文就EPC动员的影响因素及其机制进行综述。 Endothelial progenitor cells (EPCs), a class of progenitor cells originally produced in the bone marrow and able to differentiate into mature vascular endothelial cells, are involved in angiogenesis and play roles in endothelium repair and maintenance of vascular endothelium self-balance Key role. It is an effective measure to promote angiogenesis and endothelial repair by stimulating the mobilization of endothelial progenitor cells and increasing the number of circulating endothelial progenitor cells. This article reviews the factors and mechanisms of EPC mobilization.