本文合成了聚苯乙烯型阳离子交换树脂和载铁的胺基膦酸螯合树脂,前者为降钾树脂,后者为降磷树脂。研究了这两种树脂分别对血钾和血磷的交换性能。经动物试验和临床初步应用表明,这两种树脂去除量高(每克降钾树脂可交换钾离子45毫克以上,每克降磷树脂可去除磷12毫克以上)、无毒、无致敏性质、无致癌作用、治疗效果良好。现已试验性地应用在肾衰竭患者高钾血症和高磷血症的治疗中。 This paper synthesized a polystyrene-based cation exchange resin and iron-loaded amine-based phosphonic acid chelating resin, the former is potassium-reducing resin, the latter for the phosphorus-lowering resin. The exchange performance of the two resins on serum potassium and phosphorus respectively was studied. Animal experiments and preliminary clinical applications show that the removal of these two resins is high (potassium per gram of potassium exchange resin can exchange more than 45 mg per gram of phosphorus resin can remove more than 12 mg), non-toxic, non-allergenic , No carcinogenic effects, the treatment effect is good. Has now been used experimentally in the treatment of hyperkalemia and hyperphosphatemia in patients with renal failure.