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一、垂体激素胎儿窘迫时起重要作用的是ACTH,在妊娠第11周人胎血中,就能发现ACTH,随妊娠进展浓度上升。32~34周左右最高,以后慢慢下降。虽还未见到处于窘迫时胎儿ACTH的动态报导,但Arai曾报告,分娩时胎儿头皮血及分娩后当时脐带血,与分娩之进展相应呈现高值,此即反应分娩的应激作用,胎儿垂体分泌ACTH的量增加,当然加上强度应激的胎儿窘迫状态,ACTH就更加亢进。Jones将羊置于9%O_2,3%CO_2,88%N_2之状态下,观察缺O_2状态下胎仔血中ACTH浓度之变化。妊娠后半期之胎仔,60分钟缺O_2,ACTH上升。其上升之幅度与胎仔缺O_2解除后心搏数增
First, the pituitary hormone plays an important role in fetal distress is ACTH, in the first 11 weeks of pregnancy in fetal blood, you can find ACTH, with the progress of pregnancy increased concentration. 32 to 34 weeks or so the highest, then slowly decline. Although there is no dynamic report of fetal ACTH in distress, Arai has reported that fetal scalp blood at childbirth and cord blood after delivery have a high value corresponding to the progress of childbirth, which reflects the stress response of childbirth Pituitary ACTH secretion increased, of course, coupled with the intensity of stress fetal distress, ACTH even more hyperthyroidism. Jones placed 9% O_2, 3% CO_2, and 88% N_2 into the sheep to observe the change of ACTH in fetal blood without O_2. The second trimester of pregnancy, lack of O 2 60 minutes, ACTH increased. The rate of increase and fetal lack of O 2 after the lifting of the heart rate increased