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中药桔梗为桔梗科植物桔梗(Platycodongrandiflorum)的根。传统的炮制方法是刮去外皮,洗净晒干。刮皮后约耗药材10~15%,而且还耗资费力。贵州省每年收购桔梗约8000 担,在保证药效不增加毒性的条件下,如果能够不刮皮,每年可节约大批人力和资金。为此,我们受省药材公司的委托,对同一批新鲜桔梗干品,从祛痰和毒性等几个方面进行了实验比较。结果表明,去皮和不去皮桔梗在上述药理作用方面相似,因此认为不去皮桔梗可以代替去皮桔梗入药。一、祛痰实验方法:小鼠酚红法,见文献。结果:见表1。
Traditional Chinese medicine Platycodon grandiflorum Platycodonrandiflorum root. The traditional method is to scrape off the skin, wash and dry. About 10 to 15% of medicinal materials are consumed after shaving, and it is also costly and laborious. Each year, Guizhou Province purchases about 8,000 brachycodons, and if it can ensure that the efficacy does not increase the toxicity, if it can not scrape the skin, it will save a large amount of manpower and funds each year. For this purpose, we were commissioned by the Provincial Medicine Company to conduct an experimental comparison of the same batch of fresh Campanulaceae dry products from the aspects of pupa and toxicity. The results showed that the peeling and non-peeling of Platycodon grandiflora were similar in the pharmacological effects mentioned above, and therefore it was considered that peeled Platycodon grandiflorum could be used instead of peeled Platycodon as medicine. First, the experimental method: mouse phenol red method, see the literature. Results: See Table 1.