随着牙鲆工厂化养殖及海水网箱养殖规模的不断扩大,各种疾病开始频繁发生,其中以牙鲆腹水病的危害最为严重,该病从苗种到成鱼均有发生,死亡率可达50%-80%,而且尚无有效的治疗方法,因此,给养殖者造成巨大经济损失。根据国内外研究发现,牙鲆鱼腹水病的病原菌为迟钝爱得华氏菌和嗜水气单胞菌。本研究系统地完成了病原菌的分离、纯化、人工感染、生理生化测定,同时,进行了药敏试验及防治试验,在理论上为牙鲆疾病的研究奠定了基础,在实践中为大规模养殖牙鲆提供了比较有效的防治方法。 With the Japanese flounder factory farming and the continuous expansion of the scale of marine cage culture, a variety of diseases begin to occur frequently, of which the disease is most serious ascites disease, the disease occurs from seed to adult fish have occurred, the mortality rate can be Up to 50% -80%, and there is no effective treatment, therefore, causing great economic losses to farmers. According to the research at home and abroad, it is found that the pathogen of flounder and asparagus is Aspergillus fumigatus and Aeromonas hydrophila. In this study, the isolation, purification, artificial infection and physiological and biochemical determination of pathogenic bacteria were systematically carried out. At the same time, drug susceptibility testing and prevention and control tests were carried out, which laid the foundation for the research on diseases of Japanese flounder in theory. In practice, Flounder provides a more effective method of prevention and treatment.