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目的探讨呼吸(有创呼吸机)支持治疗COPD并发肺性脑病临床治疗效果。方法回顾分析2007年12月至2012年1月我院呼吸内科治疗228例COPD并发肺性脑病按是否给予呼吸支持(有创呼吸机)治疗分为治疗组和非治疗组,分析比较两组的住院天数、治愈率以及死亡率。并对效果采用统计学分析。结果按GOS标准;治疗组经过呼吸支持治疗和抗生素、糖皮质激素、氨茶碱、沙丁胺醇等治疗COPD并发肺性脑病后的住院天数是(10.26±0.66)d明显少于非治疗组(21.12±1.40)d(P<0.05);治愈率:治疗组为89.71%明显高于非治疗组治愈率13.20%(P<0.05);死亡率:治疗组为5.71%明显少于非治疗组死亡率84.90%(P<0.05)。结论及时有效的呼吸支持(有创呼吸机)治疗和抗生素、糖皮质激素、氨茶碱、沙丁胺醇等治疗COPD并发肺性脑病,可有效地控制病情,提高治愈率,降低住院天数和降低死亡率。
Objective To investigate the clinical effect of respiration (invasive ventilator) in the treatment of COPD complicated with pulmonary encephalopathy. Methods Retrospective analysis of December 2007 to January 2012 in our hospital respiratory medicine treatment of 228 cases of COPD with pulmonary encephalopathy according to whether to give respiratory support (invasive ventilator) treatment is divided into treatment group and non-treatment group, analysis and comparison of two groups Length of stay, cure rate, and death rate. And the effect of using statistical analysis. Results According to the GOS standard, the hospitalization days after treatment of respiratory support and antibiotics, glucocorticoids, aminophylline and albuterol in patients with COPD complicated by pulmonary encephalopathy were significantly lower in the treatment group (10.26 ± 0.66) d than those in the non-treatment group (21.12 ± 1.40) d (P <0.05). The cure rate was 89.71% in the treatment group and 13.20% in the treatment group (P <0.05). The mortality rate was 5.71% in the treatment group and 84.90% in the non-treatment group % (P <0.05). Conclusions The timely and effective treatment of respiratory support (invasive ventilator) and antibiotics, glucocorticoids, aminophylline, albuterol and albuterol in the treatment of COPD complicated with pulmonary encephalopathy can effectively control the condition, improve the cure rate, reduce the length of hospital stay and reduce the mortality rate .