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目的:评价全球7种主要退行性疾病负担,归纳临床常用的治疗药物特点,为保健资源的合理利用提供参考。方法:通过检索美国华盛顿大学IHME网站、世界卫生组织(WHO)官网的相关数据,查阅美国食品药品监督管理局(FDA)网站,评价主要退行性疾病负担,总结近几年上市的以及常用治疗药物的特点。结果:伴随着全球预期寿命延长,与年龄相关的退行性疾病的负担呈增长趋势,相比肿瘤、糖尿病和心血管疾病,新研发上市的老年退行性疾病治疗药物甚少。结论:建议加强保健资源利用,提升健康素养,以减轻家庭负担。
OBJECTIVE: To evaluate the burden of seven major degenerative diseases in the world and summarize the characteristics of commonly used therapeutic drugs in clinic so as to provide reference for the rational utilization of health care resources. METHODS: By retrieving data from the IHME website of the University of Washington and the World Health Organization (WHO) website, consult the FDA website to assess the major degenerative diseases burden and to summarize the data on the listed and commonly used medications in recent years specialty. RESULTS: With an increase in global life expectancy, the burden of age-related degenerative diseases is on the rise. Few new treatments for degenerative diseases are listed on the market compared to oncology, diabetes and cardiovascular disease. Conclusion: It is recommended to strengthen the utilization of health care resources and improve the health literacy so as to reduce the burden on families.