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目的探讨幽门螺杆菌感染对儿童慢性胃炎胃肌电活动的影响。方法通过幽门螺杆菌(HP)检测及组织病理学检查,将47例慢性胃炎患儿分为HP阳性组和HP阴性组,对各组患儿进行胃电图(EGG)检测。HP阳性患儿予克拉霉素15mg/(kg.d),阿莫西林50 mg/(kg.d),奥美拉唑0.8 mg/(kg.d)三联抗HP治疗2周,其中HP根除者再行胃电图检测。结果HP阳性组和HP阴性组胃电图参数值比较无显著差异,HP阳性组抗HP治疗前餐前主功率明显低于治疗后(t=2.197,P<0.05)。结论HP感染对慢性胃炎儿童胃肌电活动存在一定影响。
Objective To investigate the effect of Helicobacter pylori infection on gastric myoelectrical activity in children with chronic gastritis. Methods Helicobacter pylori (HP) and histopathological examination were used to divide 47 children with chronic gastritis into HP positive group and HP negative group, and EGG was detected in each group. HP-positive children with clarithromycin 15mg / (kg.d), amoxicillin 50 mg / (kg.d), omeprazole 0.8 mg / (kg.d) triple anti-HP treatment for 2 weeks, of which HP eradication Those who go to the stomach electrogram detection. Results There was no significant difference in the parameters of electrogastrogram between HP positive group and HP negative group. The pre-meal main power of HP positive group was significantly lower than that before treatment (t = 2.197, P <0.05). Conclusion HP infection has some effect on gastric myoelectrical activity in children with chronic gastritis.