论文部分内容阅读
炎症在糖尿病肾病的发生发展中具有重要意义。体外、动物及临床试验均证实炎症与糖尿病肾病关系密切,二者相辅相成,形成恶性循环。既往研究主要集中在血糖、血脂代谢紊乱和血流动力学异常等方面,近来越来越多的实验与临床研究表明炎症是糖尿病肾病发生与持续进展的关键因素,本文概述了糖尿病肾病发病炎症机制及干预措施,为进一步延缓或逆转糖尿病肾病的进展提供新的方向。
Inflammation is of great importance in the occurrence and development of diabetic nephropathy. In vitro, animal and clinical trials have confirmed that inflammation and diabetic nephropathy are closely related, the two complement each other to form a vicious circle. Previous studies mainly focused on blood glucose, dyslipidemia and hemodynamic abnormalities, etc. More and more recent experimental and clinical studies have shown that inflammation is a key factor in the occurrence and progression of diabetic nephropathy. This article provides an overview of the pathogenesis of diabetic nephropathy And interventions to provide a new direction for further delay or reverse the progress of diabetic nephropathy.