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目的分析胎儿第五、六脑室扩张的超声表现及其临床结果 ,探讨第五、六脑室扩张在产前遗传咨询及新生儿预后的临床意义。方法对孕中晚期胎儿常规探测第五、第六脑室,对存在脑室扩张胎儿进行系统的产前超声检查,建议行胎儿染色体及病毒学检查,产后行新生儿头颅超声检查,定期随访。结果本次研究的胎儿第五、第六脑室扩张孕妇共95例,发生率为0.86%,其中单纯第五脑室扩张52例,单纯第六脑室扩张17例,合并第五、第六脑室扩张26例。脑室扩张部位以及扩张程度与围生期结局无明显关系(P<0.05),但产后脑室扩张恢复正常的正常围生儿例数显著高于脑室扩张程度增加的正常围生儿例数(P>0.05)。结论胎儿期第五、第六脑室扩张这一超声征象在产前超声检查中应引起足够的重视。
Objective To analyze the ultrasonographic features and clinical results of the fifth and sixth ventricular dilations in fetuses and to explore the clinical significance of the fifth and sixth ventricle dilatation in prenatal genetic counseling and neonatal prognosis. Methods The fetuses in the second trimester were routinely detected in the fifth and the sixth ventricle. Prenatal ultrasound was performed on fetuses with ventricular dilatation. Fetal chromosomal and virological examination was recommended. Postnatal neonatal head ultrasound was performed and followed up regularly. Results In this study, there were 95 pregnant women with the fifth and sixth ventricle dilatation in this study, the incidence rate was 0.86%. Among them, only the fifth ventricle dilated in 52 cases, the simple sixth ventricle dilated in 17 cases and the fifth and sixth ventricle dilated 26 example. The number of ventricular dilatation sites and extent of expansion had no significant correlation with perinatal outcome (P <0.05), but the number of normal perinatal children with normal postnatal ventricular dilatation was significantly higher than that of normal perinatal patients with increased ventricular dilatation (P> 0.05). Conclusions The fifth and sixth ventricular dilatation in fetuses should be given enough attention in prenatal ultrasonography.