【摘 要】
：
A light-promoted metal-free protocol for the amination of imidazo[1,2-a]pyridines with N-aminopyridinium salt by the assistance of surfactants in water was reported,charactering mild and environmentally benign conditions,as well as great functional group
【机 构】
：
Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs,School of Life Science
论文部分内容阅读
A light-promoted metal-free protocol for the amination of imidazo[1,2-a]pyridines with N-aminopyridinium salt by the assistance of surfactants in water was reported,charactering mild and environmentally benign conditions,as well as great functional group toler-ance.Micelles with negatively charged polar surface and hydrophobic core formed from sodium dodecyl sulfate serve as an ideal me-dium for visible-light mediated radical reaction of cationic pyridine salt and imidazo[1,2-a]pyridine in aqueous phase.The electrostat-ic interaction between positively charged N-aminopyridinium and negatively charged surface of micelles is of great significance in this method.
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