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肺是花生四烯酸(AA)代谢很活跃的器官。这些代谢物不仅参与气道及肺血管的体液控制,还参与病理刺激作用下所发生的肺循环及气道的某些反应。AA 的环加氧酶途径产物前列环素(PGI_2)进入体循环还可能影响或调制肺外器官的机能。
Lung is an organ that is metabolized by arachidonic acid (AA). These metabolites are involved not only in the body fluid control of the airways and pulmonary vessels, but also in the pulmonary circulation and certain reactions of the airways that occur under the pathological stimuli. The entry of cyclooxygenase pathway product PG (PGI2) into the systemic circulation of AA may also affect or modulate the functioning of extrapulmonary organs.