细胞粘附分子(cell adhesion molecules,CAMs)是位于细胞膜表面的糖蛋白。CAMs通过介导细胞与细胞、细胞与细胞外基质间的相互作用,参与多种生理及病理过程。近年来研究发现,人类子宫内膜的腺上皮及基底膜均有多种CAMs的表达,有些呈周期性变化,并与子宫内膜“着床窗”的开放同步。某些CAMs的异常表达可能参与了子宫内膜异位症的发病过程,并可通过干扰子宫内膜的接受性导致部分患者不孕。 Cell adhesion molecules (CAMs) are glycoproteins located on the surface of cell membranes. CAMs participate in a variety of physiological and pathological processes by mediating cell-cell, cell-extracellular matrix interactions. In recent years, studies have found that human endometrial glandular epithelial and basement membrane expression of a variety of CAMs, some cyclical changes, and with the endometrium “implantation window” open synchronization. Abnormal expression of some CAMs may be involved in the pathogenesis of endometriosis and may lead to infertility in some patients by interfering with endometrial receptivity.